Her rheumatologist instructed her to undergo a baseline ocular examination prior to initiating Plaquenil (hydroxychloroquine, Sanofi-Aventis) therapy. Toxic maculopathy associated with chloroquine use was first documented in the literature five decades ago.1 In the United States, Plaquenil––an analog to chloroquine––is used to treat a variety of conditions, including rheumatoid arthritis, lupus and several distinct inflammatory disorders. Although the incidence of macular toxicity is infrequent with Plaquenil use (at a dosage of 200mg or 400mg q.d.), its visual impact can be devastating. Osteoarthritis joint nodules hydroxychloroquine Chloroquine 250 mg tablet Chloroquine and osmotic lysis of endosome One of the reasons that physicians feel comfortable in prescribing Plaquenil is its low risk to benefit ratio. This means that the side effects of Plaquenil are mild and infrequent compared with its potential benefits. As with any medication, allergic reactions including skin rashes and non-allergic reactions can occur. Or higher - up to 400 mg Plaquenil daily; 5’ 1/2” to 5’ 6 1/2” - up to 300 mg Plaquenil daily; 5’ or shorter - up to 200 mg Plaquenil daily; Women with lupus who are AT OR BELOW their ideal body weight should go by these dosing rules 135 lbs. or more, any height - up to 400 mg Plaquenil daily Just wondering if anyone on plaquenil has experienced getting more floaters, light sensitivity or any other effects on the eyes, because I think that is what is starting to happen to me now that I have been on it for 10 months? Is it possible that it can start affecting the eyes more as time goes on? Any feedback would be great? Initially, central visual acuity may be unaffected, but the patient may notice related paracentral scotomas that often interfere with reading. The associated classic retinal toxicity is described as a bull’s eye maculopathy (ring of depigmented retinal pigment epithelium that spares the foveal area). Plaquenil eye light sensitivity Will you have Photosensitivity reaction with Plaquenil., Protecting your eyesight when taking Plaquenil Lupus. Plaquenil freshnessSynthesis of chloroquine from m-chloroanilineChloroquine for malaria prophylaxis dosingHydroxychloroquine bluelightHydroxychloroquine drug guide Many people take Plaquenil for many years without any ill effects. The eye issues they are careful to warn about are actually very rare, and are even reversible, so as long as you get the appropriate eye exam once a year the risk is very, very small. Dry eyes, Sjogren’s and Plaquenil. -. Can plaquenil cause eye floaters? -. Plaquenil Las Vegas Diabetic Retinopathy Wellish Vision Institute. Light sensitivity, seeing halos around lights, pale skin, easy bruising or; bleeding, confusion, unusual thoughts or behavior, or; seizures convulsions. Dosage for Plaquenil. The adult dose of Plaquenil to suppress malaria is 400 mg on the same day each week. The pediatric weekly suppressive dosage is 5 mg/kg of body weight. Light Sensitivity and Lupus Medications. Certain medications used to treat lupus may also exacerbate light sensitivity, such as plaquenlil also known as hydroxychloroquine. 2 Oftentimes, these are rare side effects and should not deter you from appropriate treatment, but it is important to be aware of what might result from their usage. More in Eye Health. If you are taking Plaquenil to treat an inflammatory condition or malaria, you should be aware of the side effects that may occur to your eyes and vision. Plaquenil hydroxychloroquine is in a class of drugs called disease-modifying anti-rheumatic drugs, which are used to decrease inflammation, pain and joint damage.