Although not all of these side effects may occur, if they do occur they may need medical attention. Check with your doctor immediately if any of the following side effects occur while taking hydroxychloroquine: Incidence not known Some side effects of hydroxychloroquine may occur that usually do not need medical attention. Plaquenil tablets covis Does plaquenil cause leg pain Plaquenil for joint pain in oeds Plaquenil visual side effects Severe depression and anxiety, overall itching, pain and stiffness increased instead of decreased First, my mother and sister took plaquenil for lupus with good effect, so I am not just disliking it for no good reason. I also suffer from disabling bipolar disorder. For 25 years, I have gotten hypomanic during spring. Very happy, never depressed. Side Effects Nausea, stomach cramps, loss of appetite, diarrhea, dizziness, or headache may occur. If any of these effects persist or worsen, notify your doctor or pharmacist promptly. Remember. Many doctors disagree about the effects of plaquenil on the arthritis. It does help in about 60 % of the cases of arthritis by significantly reducing the pain. However, about 20 – 30 percent of people stop using it because of the side effects. Side effects include digestive problems, skin rash and disorders of skin pigmentation. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. These side effects may go away during treatment as your body adjusts to the medicine. Plaquenil side effects anxiety Plaquenil, anxiety and depression,, Plaquenil Oral Uses, Side Effects, Interactions. Does hydroxychloroquine cause vision lossHydroxychloroquine eyes treatmentPlaquenil 200 mg wikipediaGeneric plaquenil uses Get medical help right away if you have any very serious side effects, including sensitivity to light, vision changes e.g. blurred vision, seeing light flashes/streaks/halos, missing/blacked-out areas of vision, muscle weakness, numbness/tingling/pain of the arms/legs. Plaquenil Oral Uses, Side Effects, Interactions, Pictures.. Side effects of Plaquenil Other Drugs discussions.. Plaquenil Side Effects Common, Severe, Long Term -. SIDE EFFECTS Nausea, stomach cramps, loss of appetite, diarrhea, dizziness, or headache may occur. If any of these effects persist or worsen, notify your doctor or pharmacist promptly. Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Re Plaquenil Side Effects of Anxiety and Depression? Hi, I was at my most anxious as my rashes, fatigue, pain, GI & urinary issues, headaches, etc. were on the rise, and I was also in perimenopause at the time. Serious side effects and their symptoms can include the following blurred vision or other vision changes. ringing in your ears or hearing loss. angioedema, or rapid swelling of your skin. hives. mild or severe bronchospasm that causes trouble breathing. sore throat. unusual bleeding or bruising.