If the disease affects your mucous membranes, it tends to be more resistant to treatment and prone to recur. Whatever treatment you use, you'll need to visit your doctor for follow-up appointments about once a year. Plaquenil chpl Sandoz plaquenil Plaquenil cause hyperpigmentation Of all the alopecias, both non-scarring and scarring, lichen planopilaris is the most difficult to treat. There have been no well-controlled trials documenting the benefit of any therapy in LPP. Since there is no possibility of regrowth in the scarred areas, the goal of treatment is to prevent enlargement of the scarred areas and to prevent new areas of inflammation from developing. Hydroxychloroquine is a type of anti-inflammatory medication used to treat some types of hair loss such as lichen planopilaris and sometimes discoid lupus and frontal fibrosing alopecia. It is classified as an anti malarial pill because certain closely related medications i.e. chloroquine are actually used to treat malaria infections in some parts of the world. Successful treatment of actinic LP was occasionally reported with the use of hydroxychloroquine sulfate, 200 to 400 mg/d, 61-64 but often in association with topical corticosteroids. In 1 patient, 65 LP involving the nails was cleared with chloroquine hydrochloride only. The first choice for treatment of lichen planus is usually a prescription corticosteroid cream or ointment. Medications and other treatments might help relieve itching, ease pain and promote healing. Talk with your doctor to weigh the potential benefits against possible side effects of treatment. Hydroxychloroquine lichen planopilaris I have lichen planopilaris and the doctor is recommending treatment., Hydroxychloroquine Plaquenil — Canadian Hair Loss. Plaquenil indications Lichen planopilaris LPP is a rare chronic scarring folliculitis of the scalp of unknown cause Figure 1. It is considered a primary scarring alopecia since the follicle itself is targeted by inflammatory cells and scarring occurs first and primarily around the follicular unit. Lichen Planopilaris - Dermatology Advisor. Treatment of Lichen Planus An Evidence-Based Medicine.. Lichen Planopilaris - Pictures, Causes, Treatment, Diagnosis. An analysis of computerized medical records for 32 patients who had been treated for lichen planopilaris at a tertiary referral hair center in Australia was conducted from 2012 to 2016 by Dr. Kerkemeyer of the University of Notre Dame Australia, Werribee, and Jack Green, MD, of the Skin and Cancer Foundation and St. Vincent’s Hospital in Melbourne. The study excluded patients with a dual diagnosis, or those followed for less than 12 months. Hydroxychloroquine Plaquenil® is a 4-amino-quinoline antimalarial medication that is widely used to treat systemic lupus erythematosus SLE, rheumatoid arthritis, and related inflammatory and dermatological conditions. It is a hydroxylated version of chloroquine, with a similar mechanism of action. A variety of systemic agents are used to treat lichen planopilaris LPP with a limited evidence base. The aim of our study was to retrospectively review the response rate to and tolerability of hydroxychloroquine in a cohort of patients with LPP in an effort to add to the evidence base for its use.