Pattern of Retinopathy: Although the locus of toxic damage is parafoveal in many eyes, Asian patients often show an extramacular pattern of damage. Dose: We recommend a maximum daily HCQ use of 5.0 mg/kg real weight, which correlates better with risk than ideal weight. Plaquenil drug monograph Plaquenil for aps during pregnancy Hydroxychloroquine 200mg twice a dy And screening for hydroxychloroquine retinopathy should be given to all patients. GPP All patients should undergo 10-2 Humphrey visual fields testing using a white stimulus, followed by pupillary dilation and imaging with both spectral domain optical coherence tomography SD-OCT and widefield fundus autofluorescence FAF. B Your doctor has prescribed hydroxychloroquine also called Plaquenil® to help manage your. condition. It is a very safe and effective drug but, like all medicines, it can cause side effects. Hydroxychloroquine retinopathy. It is known that some people who take. hydroxychloroquine for more than five years and/or in high doses are at. Dence of hydroxychloroquine maculopathy. Table. Clinical, High-Speed Ultra–High-Resolution Optical Coherence Tomography, and Multifocal Electroretinogram Findings From Patients Receiving Hydroxychloroquine Patient No./ Age, y Hydroxychloroquine Dosage, mg/d Diagnosis Treatment, y Symptoms Visual Acuity, OD, OS Color Vision Visual Fields mfERG. Risk of Toxicity: The risk of toxicity is dependent on daily dose and duration of use. There are no similar demographic data for CQ, but dose comparisons in older literature suggest using 2.3 mg/kg real weight. Plaquenil retnopathy oct Hydroxychloroquine Retinopathy Still Alive and Well - The., Eye screening for patients taking hydroxychloroquine Plaquenil® Treatment for chloroquine itchingWhat test is used when you take plaquenilPlaquenil w o maculopathyTurmeric with plaquenil Diagnosis Hydroxychloroquine-induced retinal toxicity Discussion. Chloroquine CQ and hydroxychloroquine Plaquenil HCQ have been used for many years, initially for the treatment of malaria but now more commonly for the treatment of inflammatory diseases such as rheumatoid arthritis and lupus 1. Hydroxychloroquine Plaquenil Toxicity and Recommendations.. CLINICAL SCIENCES High-Speed Ultra–High. - oct-. Protecting your eyesight when taking Plaquenil Lupus.. The study findings revealed that when hydroxychloroquine was used at doses 5mg /kg, the risk of retinopathy was 1% in the first 5 yrs. 2% in 10 yrs. 20 % after 20 yrs. There was a dose response, such that those receiving doses greater that 5 mg / kg had the greatest risk of retinal toxicity. To detect chloroquine toxicity, the American Academy of Ophthalmology recommends performing fundus examinations, 10-2 automated visual fields, and at least one objective test multifocal electroretinography mfERG, fundus autofluorescence imaging, or spectraldomain optical coherence tomography SD-OCT. 1 By contrast, Amsler grid testing. Nov 01, 2015 Hydroxychloroquine Maculopathy An Update on Screening and Diagnosis A brief guide for imaging SHIRI SHULMAN, MD. H ydroxychloroquine HCQ; Plaquenil, Sanofi, Bridgewater, NJ is an antimalarial agent that is also commonly used as a treatment for a variety of rheumatologic and dermatologic conditions, such as rheumatoid arthritis and systemic lupus erythematosus.