The first antibiotic, penicillin, was discovered in 1927 by Alexander Fleming. Since then, antibiotics have saved millions of lives across the globe. What eye exams do you need for plaquenil Chloroquine diphosphate mechanism of action Rheumatoid arthritis is a chronic disorder for which there is no known cure. Fortunately in the last few years, a shift in strategy toward the earlier institution of disease modifying drugs and the availability of new classes of medications have greatly improved the outcomes that can be expected by most patients. Nothing safer Plaquenil is also known as hydroxychloroquine, so the parent drug Chloroquine can be substituted. But Chloroquine has significantly higher rate of retinal toxicity, so it isn't used much anymore. Also, Plaquenil appears to effectively reduce flares in patients with lupus not necessarily by suppressing immunity. I "know" I need some meds, but cannot tolerate Plaquenil. Wondering if anyone has come across something "natural" that mimics it. Thanks & LIGHT*****carole - Hi, Carole. When I started Plaquenil, my GI system was in an uproar. But it usually was anyway. I didn't realize, until I saw Dr. Fortunately, there exist natural alternatives that are relatively more powerful in a way that no strain of bacteria ever becomes resistant to them. Although they have beneficial effects, they have been hackneyed that new strains of bacteria resistant to these medicines were born and are now widespread. Natural alternatives to hydroxychloroquine NaturalNewsBlogs 6 Powerful Natural Alternatives To., Plaquenil substitute - Things You Didn’t Know Hydroxychloroquine mechanism rheumatoid arthritisPlaquenil retinopathy visual fieldChloroquine diphosphate A study published in 2000 showed that nearly 50% of British lupus patients had used alternative medical therapies, the most popular forms being relaxation techniques, massage and herbal medicine Table 1. Whilst it is apparent that a large number of patients are using alternative and complementary treatments, the reasons for this are less clear. Alternative and Complementary Medicine in the Treatment of.. Natural" alternative to Plaquenil. - HealthBoards. Medications used to treat lupus Lupus Foundation of America. I have taken Plaquinel/hydroxychloroquine at a low dose as maintenance for my SLE for over 20 years. No side effects. No problems. Until I went on Medicare and they don't want to pay for it. They want me to try cheaper alternatives before they will pay for hydroxychloroquine. Research on Natural and Alternative Therapies. Researchers continue to explore the benefits of alternative and complimentary therapies. There have been a number of studies that show that tai chi and yoga are effective in improving physical function in adults with rheumatoid arthritis and fibromyalgia. Exercises like tai chi and yoga, which. I'm still searching for that magic "all natural" replacement since I cannot tolerate plaquenil. The stomach, liver & eye complications are too great to bear. and that's at the lowest, lowest dose. Anyway, guess I need to get into some deeper research about exactly what this drug does, and.