Severe malaria should be treated with intravenous (IV) antimalarial medications. As a result, CDC is providing IV artesunate for the treatment of all severe malaria cases. With the discontinuation of IV quinidine, IV artesunate is now the first-line drug for treatment of severe malaria in the United States. Eye damage from plaquenil Chloroquine drug info Plaquenil and burning eyes While timely delivery of IV artesunate is anticipated, healthcare providers should consider treating the patient with an oral treatment while waiting for IV artesunate to arrive. Artemether/lumefantrine Coartem ® is the preferred antimalarial for interim treatment because of its fast onset of action. Chloroquine belongs to a group of medicines known as antimalarials. It works by preventing or treating malaria, a red blood cell infection transmitted by the bite of a mosquito. However, chloroquine is not used to treat severe or complicated malaria and to prevent malaria in areas or regions where chloroquine is known not to work resistance. Chloroquine is a medication used to prevent and to treat malaria in areas where malaria is known to be sensitive to its effects. Certain types of malaria, resistant strains, and complicated cases typically require different or additional medication. It is unknown when IV artesunate will receive FDA approval, as this process requires an interested drug company to submit a new drug application to FDA. IV artesunate is the recommended World Health Organization (WHO) first-line treatment for severe malaria but is neither FDA-approved nor commercially available in the United States. Chloroquine injection intravenous Nelbquine Chloroquine Phosphate Injection - Boditreat, Chloroquine Oral, Intramuscular Advanced. - Plaquenil drug actionMetabolic fate of chloroquineWhat people lose their hair when on plaquenil Oct 20, 2012 Quinine and chloroquine may cause potentially lethal hypotension if given by intravenous injection. Chloroquine is extensively distributed with an enormous total apparent volume of distribution Vd more than 100 L/kg, and a terminal elimination half-life of 1 to 2 months. Pharmacokinetics of Quinine, Chloroquine and Amodiaquine.. Chloroquine - Wikipedia. Where and How Chloroquine Fights Cancer Science Signaling. Chloroquine injection is used in acute attacks of malaria when the patient is unable to swallow. Dosage & administration Adult 200 to 300 mg chloroquine base by intramuscular or intravenous injection. It should not be given intravenously to children. Contraindications Infusions should be discontinued as soon as the patient is able to take chloroquine by mouth. Where facilities for intravenous infusion are not available chloroquine can be administered by intramuscular or subcutaneous injection at a dosage of 2.5 mg/kg every 4 hours or 3.5 mg/kg every 6 hours until a total of 25 mg/kg has been given. Prophylaxis Jul 30, 2019 Chloroquine belongs to a group of medicines known as antimalarials. It works by preventing or treating malaria, a red blood cell infection transmitted by the bite of a mosquito. However, chloroquine is not used to treat severe or complicated malaria and to prevent malaria in areas or regions where chloroquine is known not to work resistance.