But you may not think much about them until they hurt. To get the right treatment, you need to know the problem. If your pain is in your heel, you may have plantar fasciitis. Plaquenil eye pain Hydroxychloroquine pregnancy category Plaquenil and nerve damage - Scleroderma. This is sort of an update to the discussion I started almost a week ago about how you can tell if Plaquenil has stopped working. I went in to my Rheum this week because I was having a lot more pain, burning, and muscle fatigue, particularly in my legs and arms, especially at night while I'm trying to sleep. Talk to your doctor about this, but my guess is that the Plaquenil is not doing anything to cause the pain, but rather that it is not doing enough to prevent it. It sounds like your RA has probably gotten a bit out of control, relative, to your current treatment, and Plaquenil is not a particularly potent drug when it comes to managing joint pain. May 04, 2011 I had gone into a Rheum who tested me and put me immediately on Plaquenil. My symptoms became worse, sores in mouth, rash on chest, stomach issues, hair falling out and for some reason severe ankle pain. None of these symptoms were present prior. I stopped taking it Oct. of 2010. Usually, it hurts the worst in the morning when you’re getting out of bed. To treat it: Heel spurs are another source of foot pain. That’s an irritation or inflammation of the band of tough tissue connecting the heel bone to the toes. Plaquenil and foot pain Side Effects of Plaquenil Hydroxychloroquine, Warnings, Uses, Plaquenil and pain" Rheumatoid Arthritis Community. Plaquenil for lupus reviews fatiguePlaquenil 200mg prospect Lateral foot pain is pain that occurs on the outer edges of your feet. It can make standing, walking, or running painful. Several things can cause lateral foot pain, from too much exercise to. Lateral Foot Pain Causes, Treatment, Prevention, and More. Plaquenil and Severe Ankle Pain -. Common and Rare Side Effects for Plaquenil Oral. I'm currently taking plaquenil and tramadol, but am having so much pain in my feet, ankles, knees and wrists. I've tried heat, ice, massage, motrin, etc. and nothing seems to help. Does someone have a secret remedy to deal with this pain? Hydroxychloroquine Plaquenil is commonly used for treating joint pain in Sjögren’s syndrome patients, based in part on its efficacy in treating the joint pain of patients with systemic lupus erythematosus and rheumatoid arthritis. Plaquenil is prescribed as a disease-modifier, in other words, to decrease pain, decrease swelling, and prevent joint damage and disability. It is not known how Plaquenil works but researchers believe that Plaquenil interferes with communication between cells within the immune system. Ultimately, it is thought to block proinflammatory.