Plaquenil is used to treat or prevent malaria, a disease caused by parasites that enter the body through the bite of a mosquito. Malaria is common in areas such as Africa, South America, and Southern Asia. Hydroxychloroquine sulphate mechanism of action Hydroxychloroquine dose sle No one NSAID has been demonstrated to be better than another for the treatment of rheumatoid arthritis nor have the COX-2 agents been shown to be superior to traditional NSAIDS in terms of effectiveness. Usual Time to Effect Although these agents have anti-inflammatory effect within hours, a reasonable trial period is a few weeks to 1 month. The key treatments for asthma are steroids and other anti-inflammatory drugs. These asthma drugs both help to control asthma and prevent asthma attacks. Steroids and other anti-inflammatory drugs. Let's test your knowledge on common anti-inflammatory drugs that nurses must know! Included topics in this practice NCLEX quiz are corticosteroids, NSAIDs, and drugs related to chemotherapy. Plaquenil is also an antirheumatic medicine and is used to treat symptoms of rheumatoid arthritis and discoid or systemic lupus erythematosus. This medicine is not effective against all strains of malaria. Chloroquine as antiinflammatory Effects of chloroquine on viral infections an old drug against today's., Asthma, Steroids, and Other Anti-Inflammatory Drugs Plaquenil low heart rate Plaquenil is sometimes given only once per week. Choose the same day each week to take this medicine if you are on a weekly dosing schedule. Take Plaquenil with a meal or a glass of milk. To prevent malaria Start taking Plaquenil 2 weeks before entering an area where malaria is common. Continue taking the medicine regularly during your stay. Plaquenil Uses, Dosage & Side Effects -. Pharmacology Anti-inflammatory and Antineoplastic Drugs 25.. Hydroxychloroquine and Chloroquine Phosphate - RheumaKnowledgy. Hydroxychloroquine is classified as an anti-malarial drug. It is similar to chloroquine and is useful in treating several forms of malaria as well as lupus erythematosus and rheumatoid arthritis. Its mechanism of action is unknown. Malarial parasites invade human red blood cells. It is a hydroxylated version of chloroquine, with a similar mechanism of action. However, following an identical dose of hydroxychloroquine and chloroquine, tissue levels of chloroquine are 2.5 times those of hydroxychloroquine. Hydroxychloroquine is preferred due to its safer profile. Mechanism of action of hydroxychloroquine as an antirheumatic drug. Fox RI1. Author information 1Department of Rheumatology, Scripps Clinic and Research Foundation, La Jolla, CA 92037. The antimalarial agents chloroquine and hydroxychloroquine have been used widely for the treatment of rheumatoid arthritis and systemic lupus erythematosus.