It may have both an anti-spirochaete activity and an anti-inflammatory activity, similar to the treatment of rheumatoid arthritis. And caution is required if patients have certain heart conditions, diabetes, psoriasis etc. Plaquenil lupus en espanol What does plaquenil do for arthritis Side Effects Nausea, stomach cramps, loss of appetite, diarrhea, dizziness, or headache may occur. If any of these effects persist or worsen, notify your doctor or pharmacist promptly. Remember. NONE of my clothes fit and at the moment I do not have the energy to go clothes shopping. I did not make the connection between the medication and loss of appetite, I thought it was just part of the lupus flare up. I take my medication in the middle of dinner as I have milk issues and stomach issues and it seems to buffer any painful stomach pain. I started taking Plaquenil 4 weeks ago for non specific autoimmune disease as indicated by ANA. Symptoms were low grade temperature off and on for a year, joint pain and fatigue. I have already felt some relief. Some nauseau at first but less problem with fever and joint pain. But, now I have started having stomach cramps and diarrhea. I understand these may go away. Is there anything I can. The most serious adverse effects affect the eye, with dose-related retinopathy as a concern even after hydroxychloroquine use is discontinued. The most common adverse effects are a mild nausea and occasional stomach cramps with mild diarrhea. Stomach digestion meditcation plaquenil What over-the-counter medications can help with stomach pain?, Having issues with Plaquenil - Plaquenil and low neutrophilsChemical process of chloroquineSurgical chloroquine prepChloroquine heme polymeraseHydroxychloroquine mechanism of action medscape This medication is helping to alleviate the inflamation and pain. My doctor prescribed that I take it in the morning after breakfast but it made me too naueseous and made my stomach hurt because there was not enough food in my system. I switched to taking it after dinner and my experiance is much better. Plaquenil Drug and Medication User Reviews on RxList. Stomach problems with Plaquenil • Johns Hopkins Arthritis Center. Plaquenil Hydroxychloroquine Uses, Dosage, Side Effects.. Applies to hydroxychloroquine oral tablet. Along with its needed effects, hydroxychloroquine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention. Check with your doctor immediately if any of the following side effects occur while taking hydroxychloroquine Hydroxychloroquine is in a class of drugs called antimalarials. It is used to prevent and treat acute attacks of malaria. It is also used to treat discoid or systemic lupus erythematosus and rheumatoid arthritis in patients whose symptoms have not improved with other treatments. I started taking Plaquenil 4 weeks ago for non specific autoimmune disease as indicated by ANA. Symptoms were low grade temperature off and on for a year, joint pain and fatigue. I have already felt some relief. Some nauseau at first but less problem with fever and joint pain. But, now I have started having stomach cramps and diarrhea.