It's used to treat and prevent malaria infection, and to reduce symptoms and progression of autoimmune diseases such as lupus, rheumatoid arthritis, and others. Malaria is spread by mosquitoes, which transmit the parasites that cause the infection, usually in tropical and subtropical parts of the world. Plaquenil dosage based on weight Taking plaquenil and breastfeeding Chloroquine nhibts clathrin mediated endocytosis Lysosomal acidification chloroquine Plaquenil-induced erythroderma. Slagel GA, James WD. A patient who developed exfoliative erythroderma 11 days after the initiation of hydroxychloroquine treatment for psoriatic arthritis is presented. Exfoliative dermatitis, or erythroderma, is an erythematous, scaly dermatitis involving at least 90% of the skin surface. The diagnosis of exfoliative dermatitis is based on skin findings on physical examination and not on the underlying etiology for the dermatitis, which is variable and may be idiopathic see Differential Diagnosis. Some of the dosage forms listed on this page may not apply to the brand name Plaquenil. For the Consumer. Applies to hydroxychloroquine oral tablet. Along with its needed effects, hydroxychloroquine the active ingredient contained in Plaquenil may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention. For example, it may be combined with an antibiotic to treat chronic Q-fever, which humans usually catch from farm animals or raw milk. Plaquenil is used to treat other types of infections too. Plaquenil exfoliative dermatitis PLAQUENIL HYDROXYCHLOROQUINE SULFATE, USP WARNING PHYSICIANS SHOULD., Exfoliative Dermatitis Practice Essentials, Background. Hydroxychloroquine in diabetesUsual dose of plaquenilPlaquenil and parkinson'sHydroxychloroquine oral ulcersNew guidelines for plaquenil macuopathy 2018 It should be noted that 4-aminoquinolines in therapeutic doses have been associated with central nervous system damage, including ototoxicity auditory and vestibular toxicity, congenital deafness, retinal hemorrhages and abnormal retinal pigmentation. Therefore Plaquenil should not be used in pregnancy. Plaquenil 200mg Film-coated Tablets - Summary of Product.. Plaquenil Side Effects Common, Severe, Long Term -. PLAQUENIL Side Effects & Interactions RxSaver by RetailMeNot. A case of PA with development of erythroderma and exfoliative dermatitis following the use of hy- droxychloroquine is presented. The effects of an- timalarials on psoriasis are also reviewed. CASE REPORT Our patient, a 31-year-old woman, had a 19-year history of psoriasis involving the scalp, face, elbows, knees. Plaquenil is an anti-arthritis drug used to treat connective tissue disorders. What it does is make the body more alkaline. It is prescribed with Biaxin Clarithromycin-an intracellular abx a lot because by making the body more alkaline, the Biaxin can more easily penetrate the body's cells, which makes it up to 40% more effective. INDICATIONS PLAQUENIL is indicated for the suppressive treatment and treatment of acute attacks of malaria due to Plasmodium vivax, P. malariae, P. ovale, and susceptible strains of P. falciparum. It is also indicated for the treatment of discoid and systemic lupus erythematosus, and rheumatoid arthritis.