Also had to have an occupational health meeting today for my job as not worked for 6 months now and hoping they make me redundant as i can't work as a waitress with ra due to pain and flares in my opinion. (others may do) and i then can get benefits till i find a job i can do with the ra(i am not doing this just for benefits, i hope people understand that) I have now been on Plaq for just over three years and MTX for just under three years. Plaquenil and mood Plaquenil and heartburn What is Methotrexate? Methotrexate has active ingredients of methotrexate sodium. It is often used in rheumatoid arthritis. Check the latest outcomes from 354,175 Methotrexate users, or browse all drugs. What is Plaquenil? Plaquenil has active ingredients of hydroxychloroquine sulfate. It is often used in systemic lupus erythematosus. He was treated instead with low-dose oral methotrexate. Comment. Ultraviolet light is contra-indicated for patients with lupus, and prednisone is relatively contra-indicated for psoriasis. This is a case where Plaquenil likely triggered new-onset psoriasis in a patient who was genetically susceptible. Methotrexate is one of the most commonly used drugs for the treatment of rheumatoid arthritis, and it is used in lupus patients to alleviate the joint pain and swelling of polyarthritis arthritis involving multiple joints. My Rheumy suggested MTX and told me it would be months before we knew for sure it would work. The combination works well for me-though I also take a NSAID. I started feeling better about a month after starting plaq-I was also on prednisone at the time-but couldn't get all the way well. Methotrexate and plaquenil for lupus Plaquenil hydroxychloroquine sulfate dose, indications., Psoriasis Associated with Plaquenil Hydroxychloroquine. Plaquenil vomiting Lupus & methotrexate research. While lupus is not specifically approved for lupus, there have been a large number of studies that intend to measure the effectiveness of the drug for people with lupus. Some studies are quite specific, finding benefit of methotrexate for people with cutaneous lupus, antimalarial-resistant lupus arthritis, and. Methotrexate Rheumatrex for Lupus - LupusCorner. Treating Lupus with Immunosuppressive Medications Johns.. How is rheumatrex methotrexate used to treat lupus?. I know Plaquenil has helped me a ton, because I tried going off of it once to see if I really needed it. The first two weeks weren't bad, as Plaquenil has a high half-life and there was still some Plaquenil in my body. After that, my Lupus got progressively worse until I gave up and re-started the Plaquenil after 6 weeks of being off it. Plaquenil is prescribed for Lupus, RA, Sjogren's Syndrome and Joint Pain and is mostly mentioned together with these indications. Interaction between Methotrexate and Plaquenil There is no known interaction between Methotrexate and Plaquenil in our records. However, an interaction may still exist. I had a biopsy and my doctor said he believes it is morphea. I am waiting on my blood test to come back and he said as soon as it does he will put me on both methotrexate and doctor is a very good derm.