False-negatives and false-positives from immunoassays can lead to adverse consequences for patients and providers. By identifying medications that contribute to false-negatives and false-positives, pharmacists decrease misinterpretations from urine drug screens. Chloroquine preparation Plaquenil eye screening recommendations Hydroxychloroquine dose dialysis False-positive results for amphetamine and methamphetamine were the most commonly reported. False-positive results for methadone, opioids, phencyclidine, barbiturates, cannabinoids, and benzodiazepines were also reported in patients taking commonly used medications. False-positive methadone levels have been documented with diphenhydramine 100 to 200 mg 2-4,14 and doxylamine intoxication. 4,15 Additionally, doxylamine intoxication has produced false-positive opiate 14 and PCP 2 levels, and brompheniramine use may cause false-positive amphetamine 4 and LSD 3,9 levels. Consider using second-generation. Used to treat ADHD, Ritalin is a well-known cause of false positive tests for amphetamine, methamphetamine, and LSD. 12 Doxylamine. Doxylamine, found in Unisom and other over-the-counter sleep aids, may cause a false positive on drug tests for methadone, opiates, or PCP. 13 Sertraline Zoloft Sertraline is an antidepressant. Taking. Pharmacists can provide guidance in selecting appropriate drug therapies that are less likely to cause false readings, thus decreasing the need for additional testing. Unexpected results from urine immunoassays should have a confirmatory gas chromatography–mass spectrometry or a high-performance liquid chromatography test performed. Plaquenil false positive methadone Hydroxychloroquine - I believe this drug causes false., Urine Drug Screening Minimizing False-Positives and False. Hydroxychloroquine to stop flare upsHistory of chloroquineAmoxicillin and plaquenilBuy aralen 250Retinal pigment epithelial mottling of macula plaquenil False positives are a real problem at these clinics it seems. They tell me to not take any supplements such as pre-workouts. I recently had a urine sample come back positive for amphetamine. It's as caused by a herbal supplement called acacia rigidula. I couldn't have take homes until they retested. False positives Methadone - reddit. Medications That Can Cause a False Positive on Drug Tests.. Plaquenil Oral Uses, Side Effects, Interactions, Pictures.. Stars. Plaquenil is the brand name for the prescription drug hydroxychloroquine. It's used to treat and prevent malaria infection, and to reduce symptoms and progression of autoimmune diseases such as lupus, rheumatoid arthritis, and others. Some false-positive results for methadone have already been reported with other techniques and were attributable to metabolites of verapamil, diphenhydramine, or doxylamine. In our patients, these compounds are not an issue of concern. Medications common to the inpatient setting eg, quinolone antibiotics, rifampin can also result in false-positives on opiate EIA testing. 5 In addition, there are a wide variety of common medications eg, verapamil, quetiapine, diphenhydramine, doxylamine that are known to give false-positive results on methadone-specific EIA testing. 6, 7 Poppy seeds can readily result in a positive finding in standard urine EIA testing; a product of the opium poppy, these seeds contain small amounts of.