Hydroxychloroquine in rheumatoid arthritis mechanism of action

Discussion in 'Chloroquine Phosphate 500 Mg' started by TeawDoobbisee, 11-Mar-2020.

  1. polo Guest

    Hydroxychloroquine in rheumatoid arthritis mechanism of action


    Hydroxychloroquine is available as the brand-name drug Plaquenil. Generic drugs usually cost less than the brand-name version. Hydroxychloroquine may be used as part of a combination therapy.

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    Despite widespread clinical use of antimalarial drugs such as hydroxychloroquine and chloroquine in the treatment of rheumatoid arthritis RA, systemic lupus erythematosus SLE and other. Hydroxychloroquine is a disease-modifying anti-rheumatic drug DMARD approved for adults with RA. It is often given in combination with methotrexate and sulfasalazine a treatment known as triple therapy, to help slow RA disease progression for patients who do not get relief from methotrexate therapy alone. Autoimmune diseases, like rheumatoid arthritis and lupus, are linked. Facts for patients and caregivers about the DMARD drug Hydroxychloroquine Plaquenil such as usages, Today, it is used to treat rheumatoid arthritis, Discover the 5 Common Signs and Symptoms of Rheumatoid Arthritis.

    Hydroxychloroquine is used to treat lupus erythematosus and rheumatoid arthritis. It isn’t fully understood how this drug works to treat lupus erythematosus or rheumatoid arthritis. That means you may need to take it with other drugs. It treats malaria by killing the parasites that cause the disease.

    Hydroxychloroquine in rheumatoid arthritis mechanism of action

    Hydroxychloroquine TUSOM Pharmwiki, Treatments for Rheumatoid Arthritis

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  3. Hydroxychloroquine is an aminoquinoline like chloroquine. It is a commonly prescribed medication in the treatment of uncomplicated malaria, rheumatoid arthritis, chronic discoid lupus erythematosus, and systemic lupus erythematosus. Hydroxychloroquine is also used for the prophylaxis of malaria in regions where chloroquine resistance is unlikely.

    • Hydroxychloroquine - DrugBank.
    • How Does Plaquenil Work For Rheumatoid Arthritis.
    • Hydroxychloroquine Side Effects, Dosage, Uses, and More.

    Hydroxychloroquine is classified as an anti-malarial drug. It is similar to chloroquine and is useful in treating several forms of malaria as well as lupus erythematosus and rheumatoid arthritis. Its mechanism of action is unknown. Malarial parasites invade human red blood cells. Chloroquine is a medication used to prevent and to treat malaria in areas where malaria is known to be sensitive to its effects. Certain types of malaria, resistant strains, and complicated cases typically require different or additional medication. Kyburz D, Brentano F, Gay S. Mode of action of hydroxychloroquine in RA-evidence of an inhibitory effect on toll-like receptor signaling. Nat Clin Pract Rheumatol 2006; 8. Kuznik A, Bencina M, Svajger U, et al. Mechanism of endosomal TLR inhibition by antimalarial drugs and imidazoquinolines.

     
  4. MRSEO User

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  5. iguana_zz Moderator

    Plaquenil (hydroxychloroquine) belongs to a group of medicines called quinolines. Plaquenil - FDA prescribing information, side effects and uses Chloroquine - FDA prescribing information, side effects. HYDROXYCHLOROQUINE SULFATE
     
  6. InnaVi New Member

    Hydroxychloroquine Uses, Dosage & Side Effects - Hydroxychloroquine is a quinoline medicine used to treat or prevent malaria, a disease caused by parasites that enter the body through the bite of a mosquito. Malaria is common in areas such as Africa, South America, and Southern Asia. This medicine is not effective against all strains of malaria.

    HYDROXYCHLOROQUINE SULFATE Drug BNF content published.
     
  7. watson_ Moderator

    Chloroquine Phosphate Buy Chloroquine Phosphate from. Chloroquine phosphate is a 4-aminoquinoline anti-malarial and anti-rheumatoid agent, also acting as an ATM activator.

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