Although not all of these side effects may occur, if they do occur they may need medical attention. Check with your doctor immediately if any of the following side effects occur while taking hydroxychloroquine: Incidence not known Some side effects of hydroxychloroquine may occur that usually do not need medical attention. Plaquenil price increase Hydroxychloroquine dosage rheumatoid arthritis Re Plaquenil side effects. Plaquenil made me a bit nauseated in the beginning but that wnet away within a few weeks. You usually need to be on Plaquenil for a few mon ths for it to take effect. I have read several times that those going from brand name Plaquenil to generic have had problems, including flares. Side effects of Plaquenil that are different from Aralen include loss of appetite, weight loss, dizziness, spinning sensation, ringing in your ears, mood changes, nervousness, irritability, skin rash, or itching. Side effects of Aralen that are different from Plaquenil include blurred vision, changes in hair color, or muscle weakness. If you are taking Plaquenil to treat an inflammatory condition or malaria, you should be aware of the side effects that may occur to your eyes and vision. Plaquenil hydroxychloroquine is in a class of drugs called disease-modifying anti-rheumatic drugs, which are used to decrease inflammation, pain and joint damage. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. These side effects may go away during treatment as your body adjusts to the medicine. Plaquenil side effects bleeding Hydroxychloroquine Side Effects Common, Severe, Long Term., Plaquenil vs. Aralen Prescription Treatment for Malaria. Lupus nephritis and plaquenil Long-Term Side Effects of Plaquenil for Rheumatoid Arthritis. Plaquenil is the brand name of hydroxychloroquine, a drug used to prevent or treat malaria. Plaquenil is also used for long-term treatment of autoimmune diseases such as rheumatoid arthritis RA and systemic lupus erythmatosis. Long-Term Side Effects of Plaquenil for Rheumatoid.. Plaquenil Side Effects on Your Eyes and Vision. Plaquenil - Uses, Side Effects, Interactions -. Plaquenil and Vaginal bleeding between periods - from FDA reports Summary Vaginal bleeding between periods is found among people who take Plaquenil, especially for people who are 30-39 old, have been taking the drug for 1 - 2 years, also take medication Methotrexate, and have Nausea. RARE side effects. If experienced, these tend to have a Severe expression. Abnormal Liver Function Tests. Acute Liver Failure. Acute Pustular Eruptions On Skin. Bronchospasm. Decreased Blood Platelets. Decreased White Blood Cells. Hydroxychloroquine side effects. Hydroxychloroquine side effects may vary greatly from very mild side effects that go away with time to severe side effects like eye damage, ear damage, or heart problems. Some side effects may be experienced as the body adjusts to hydroxychloroquine but may diminish as the body becomes used to the drug.