Plaquenil induced cardiomyopathy

Discussion in 'Chloroquine Drug' started by ApocX, 20-Mar-2020.

  1. Grace_Grace Guest

    Plaquenil induced cardiomyopathy

    She had been taking hydroxychloroquine as a disease-modifying agent for about 15 years. A transthoracic echocardiogram showed reduced left ventricular function with an ejection fraction of 35% (A, Online Video 1).

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    We present the case of a 75-year-old woman with a medical history of rheumatoid arthritis treated with hydroxychloroquine, who was admitted with acute left-sided heart failure due to a hydroxychloroquine-induced cardiomyopathy as supported by endomyocardial biopsy. On the basis of these classic findings, a diagnosis of hydroxychloroquine cardiomyopathy was made, and the drug was discontinued. Three months later her symptoms had completely resolved. Repeat imaging using cardiac magnetic resonance demonstrated an ejection fraction of 65% D, Online Video 2. Chloroquine CQ and hydroxychloroquine HCQ are anti‐rheumatic medications frequently used in the treatment of connective tissue disorders. We present the case of a 45‐year‐old woman with CQ‐induced cardiomyopathy leading to severe heart failure.

    Periodic-acid Schiff staining showed glycogen deposition in myocyte cytoplasm. Subsequent coronary angiography revealed normal coronary arteries. Hematoxylin and eosin staining revealed myocyte vacuolization (B).

    Plaquenil induced cardiomyopathy

    Hydroxychloroquine-Induced Restrictive Cardiomyopathy in a Patient With., Hydroxychloroquine A Treatable Cause of Cardiomyopathy JACC Journal.

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  5. Clinical manifestations of antimalarial-induced cardiotoxicity can manifest as restrictive cardiomyopathy, dilated cardiomyopathy, or conduction abnormalities such as bundle branch and atrioventricular block. Patients usually present with HF symptoms. However, non-specific chest discomfort may be a presenting or coexisting feature.

    • Hydroxychloroquine-induced restrictive cardiomyopathy a case..
    • Chloroquine‐induced cardiomyopathy a reversible cause of heart failure..
    • Plaquenil Hydroxychloroquine - Side Effects, Dosage, Interactions - Drugs.

    Maliha Shaikh, Aditi Chitale, Richard Stratton, 020. Hydroxychloroquine Induced Cardiotoxicity A Rare Complication of a Common Drug. predominantly in SLE or RA patients and one in scleroderma. We report HCQ-induced dilated cardiomyopathy in a woman with SS. Methods A 52 year old woman of Iraqi origin presented with a week’s history of. PLAQUENIL hydroxychloroquine sulfate tablets is indicated for the treatment of rheumatoid arthritis, and discoid and systemic lupus erythematosus, in patients who have not responded satisfactorily to drugs with less potential for serious side effects. Genetic predisposition for HCQ‐induced cardiomyopathy was first proposed in a set of twin sisters who both suffered from SLE. 9 Chatre et al. described a case of a 61‐year‐old woman whose diagnosis of α‐galactosidase A deficiency was unmasked by chronic HCQ treatment. 10 Because Fabry disease and other lysosomal storage disorders, such.

  6. Gogi Moderator

    Chloroquine has long been used in the treatment or prevention of malaria from Plasmodium vivax, P. malariae, excluding the malaria parasite Plasmodium falciparum, for it started to develop widespread resistance to it. Amoebic Liver Abscess and treatment difficulties Features distinguishing amoebic from pyogenic liver abscess. Chloroquine in the Treatment of Amoebic Liver Abscess The BMJ
  7. newwand New Member

    To report expanded SD-OCT findings of HCQ retinopathy that may assist the clinician in earlier diagnosis. Plaquenil Uses, Dosage & Side Effects - Plaquenil Toxicity - Retina Image Bank Early Plaquenil Toxicity Detected without Bull’s Eye.
  8. antinazi New Member

    Hydroxychloroquine Plaquenil Side Effects & Dosage for Malaria Hydroxychloroquine Plaquenil is a drug that is classified as an anti-malarial drug. Plaquenil is prescribed for the treatment or prevention of malaria. It is also prescribed for the treatment of rheumatoid arthritis, lupus, and the side effects of lupus such as hair loss, joint pain, and more.

    Hydroxychloroquine Plaquenil