Malaria is common in areas such as Africa, South America, and Southern Asia. This medicine is not effective against all strains of malaria. Plaquenil rash and itching Flomax and plaquenil Following a single 200 mg oral dose of PLAQUENIL to healthy males, the mean peak blood concentration of hydroxychloroquine was 129.6 ng/mL, reached in 3.26 hours with a half-life of 537 hours 22.4 days. 50.3 ng/mL reached in 3.74 hours with a half-life of 2963 hours 123.5 days. One Plaquenil tablet contains 200 mg of hydroxychloroquine sulfate, which is equivalent to 155 mg base. Take Plaquenil with a meal or a glass of milk. Malaria. Prophylaxis Adults 400 mg 310 mg base once weekly on the same day of each week starting 2 weeks prior to exposure, and continued for 4 weeks after leaving the endemic area. Hydroxychloroquine HCQ, sold under the brand name Plaquenil among others, is a medication used for the prevention and treatment of certain types of malaria. Specifically it is used for chloroquine -sensitive malaria. Other uses include treatment of rheumatoid arthritis, lupus, and porphyria cutanea tarda. Taking hydroxychloroquine long-term or at high doses may cause irreversible damage to the retina of your eye. Hydroxychloroquine is also an antirheumatic medicine and is used to treat symptoms of rheumatoid arthritis and discoid or systemic lupus erythematosus. Plaquenil 200 mg indications Plaquenil - Uses, Side Effects, Interactions -, Plaquenil - FDA prescribing information, side effects and uses Side effects hydroxychloroquine eyesCan i take plaquenil if i have macular degeneration Maintenance dose 200 to 400 mg 155 to 310 mg base orally once a day Each dose should be taken with a meal or a glass of milk. Usual Adult Dose for Systemic Lupus Erythematosus Discoid and systemic lupus erythematosus Initial dose 400 mg 310 mg base orally once or twice a day for several weeks or months, depending on patient response Hydroxychloroquine Uses, Dosage & Side Effects -. Hydroxychloroquine - Wikipedia. Plaquenil Hydroxychloroquine - Side Effects, Dosage.. Hydroxychloroquine is taken in tablet form, with or after food. Your doctor will advise you about the correct dose. Usually you will start on a full dose of 200–400 mg daily, and later your doctor may reduce this. When your condition is very well controlled you may be advised to take hydroxychloroquine only 2–3 times per week. One PLAQUENIL tablet contains 200 mg of hydroxychloroquine sulfate, which is equivalent to 155 mg base. Take PLAQUENIL with a meal or a glass of milk. Malaria Prophylaxis. Adults. 400 mg 310 mg base once weekly on the same day of each week starting 2 weeks prior to exposure, and continued for 4 weeks after leaving the endemic area. The recommended dose of hydroxychloroquine Plaquenil in adults is 400 mg on exactly the same day of each week. The recommended weekly suppressive dose of hydroxychloroquine Plaquenil in children 6 years of age and older is 5 mg base/kg. This dose should not exceed the adult dose reg ardless of body weight.