Chloroquine vs quinine

Discussion in 'Canadian Pharcharmy' started by ezhikGn, 01-Mar-2020.

  1. Arsenij User

    Chloroquine vs quinine


    Quinine is a basic amine and is usually provided as a salt. Various existing preparations include the hydrochloride, dihydrochloride, sulfate, bisulfate and gluconate.

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    Quinine and chloroquine poisoning are characterized by severe cardiovascular toxicity resulting from sodium and potassium channel blockade, leading to hypotension, shock, arrhythmias and cardiac arrest. Quinine poisoning can cause irreversible visual loss. Hydroxychloroquine Plaquenil, chloroquine Aralen, and quinacrine Atabrine are medications that were originally used to prevent or treat malaria. However, during World War II it was also found that these medications were effective in treating the symptoms of lupus. Chloroquine is used to prevent or treat malaria caused by mosquito bites in countries where malaria is common. Malaria parasites can enter the body through these mosquito bites, and then live in body tissues such as red blood cells or the liver.

    All quinine salts may be given orally or intravenously (IV); quinine gluconate may also be given intramuscularly (IM) or rectally (PR). In the United States, quinine sulfate is commercially available in 324-mg tablets under the brand name Qualaquin.

    Chloroquine vs quinine

    History of antimalarials Medicines for Malaria Venture, Treating Lupus with Anti-Malarial Drugs Johns Hopkins Lupus.

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  7. Warning for non-medical redditors Chloroquine is promising, but it's possible to OD on it and cause blindness among other things, especially if you have certain genetics. DIY not encouraged! Is anyone researching that, or are any of the regions fighting the outbreak trying that proactively?

    • Post-exposure Chloroquine Prophylaxis COVID19.
    • Chloroquine vs Quinine -.
    • Comparative study of chloroquine and quinine on malaria..

    A severe eye problem has happened with chloroquine. This may lead to lasting eyesight problems. The risk may be higher if you have some types of eye or kidney problems. The risk may also be higher with some doses of chloroquine, if you use chloroquine for longer than 5 years, or if you take certain other drugs like tamoxifen. Quinine remained the mainstay of malaria treatment until the second half of the 20th century when the synthetic product chloroquine was invented. However, chloroquine soon started showing resistance to malaria. This has been the case with most other synthetically produced products which followed the introduction of chloroquine. Chloroquine Phosphate. Chloroquine is used to prevent or treat malaria caused by mosquito bites in countries where malaria is common. Malaria parasites can enter the body through these mosquito bites, and then live in body tissues such as red blood cells or the liver.

     
  8. ValidData User

    Hydroxychloroquine is widely used in the treatment of post-Lyme arthritis. Plaquenil Hydroxychloroquine Uses, Dosage, Side Effects. PLAQUENIL® - Food and Drug Administration Common Plaquenil side effects a study from FDA data.
     
  9. Altexiabeibra XenForo Moderator

    Macular Hole Macula and Retina Institute Most macular holes occur in the elderly. When the vitreousthe gel-like substance inside the eye ages and shrinks, it can pull on the thin tissue of the macula, causing a tear that can eventually form a small hole. Sometimes injury or long-term swelling can cause a macular hole. No specific medical problem is known to cause macular holes.

    Macular Hole in Retina New England Retina Associates