One such commonly used medication for dermatologic and rheumatologic inflammatory conditions is hydroxychloroquine (Plaquenil), a chloroquine derivative. It is used to treat many diseases including malaria, rheumatoid arthritis and systemic lupus erythematosus. Chloroquine online pharmacy What is plaquenil prescribed for Hydroxychloroquine Plaquenil is considered a disease-modifying anti-rheumatic drug DMARD. It can decrease the pain and swelling of arthritis. It may prevent joint damage and reduce the risk of long-term disability. Hydroxychloroquine is in a class of medications that was first used to prevent and treat malaria. Many systemic medications may cause retinal toxicity. One such commonly used medication for dermatologic and rheumatologic inflammatory conditions is hydroxychloroquine Plaquenil, a chloroquine derivative. It is used to treat many diseases including malaria, rheumatoid arthritis and systemic lupus erythematosus. Plaquenil-induced maculopathy is a form of retinal toxicity that is associated with long-term use of of the anti-inflammatory medication plaquenil. Optometrists and ophthalmologists need to be aware of the American Academy of Ophthalmology’s 2011 guidelines on screening for retinal toxicity associated with plaquenil. It is imperative that patients and physicians are aware of and watch for this drug’s ocular side effects. Retinal toxicity from hydroxychloroquine is rare, but even if the medication is discontinued, vision loss may be irreversible and may continue to progress. Plaquenil premaculopathy Hydroxychloroquine And Chloroquine Screening 2016 AAO Recommendations., Hydroxychloroquine-Induced Retinal Toxicity - American Academy of. Methotrexate sulfasalazine and hydroxychloroquinePlaquenil ophthalmologist or optometristChloroquine resistance 2017Plaquenil and touble eye focusPlaquenil interactions with other drugs Problems with Plaquenil Use Toxic maculopathy associated with chloroquine use was first documented in the literature five decades ago.1 In the United States, Plaquenil––an analog to chloroquine––is used to treat a variety of conditions, including rheumatoid arthritis, lupus and several distinct inflammatory disorders. New Plaquenil Guidelines -. Plaquenil-Induced Toxic Maculopathy - Decision-Maker PLUS. PDF Multifocal ERG Guiding Therapy in a Case of.. To report expanded SD-OCT findings of HCQ retinopathy that may assist the clinician in earlier diagnosis. To characterize structural changes of HCQ retinopathy with SD-OCT after drug cessation. Setting Private practice and academic institution. Patient Population Patients at New England Eye Center and Ophthalmic Consultants of Boston in Boston, MA diagnosed with HCQ retinopathy and followed. Hydroxychloroquine Retinopathy - Premaculopathy, part B This 46 year old woman with systemic lupus erythematosus had taken HC for 7 years at 400 mg/d and stopped because of inadequate response. Three years later she was interested in restarting the drug and was seen for clearance. Paracentral scotoma to red targets, sometimes termed PREMACULOPATHY, is indicative of early retinal dysfunction and is usually reversible with cessation of therapy. References Ehrenfeld M, Nesher R, Merin S "Delayed-onset chloroquine retinopathy."