It may be effective in a variety of upper and lower respiratory tract infections, kidney and urinary tract infections, gastrointestinal tract infections, skin and wound infections, sepsis, and other infections caused by sensitive organisms. Co-trimoxazole decreases the risk of recurrence of retinochoroiditis. Plaquenil ful fiel derg severe Plaquenil retinopathy autofluorescence Chloroquine depensed to us troop in honduran Plaquenil for arthritis Glaser C, et al. Whipple's disease mimicking rheumatoid arthritis can cause misdiagnosis and treatment failure. Orphanet Journal of Rare Diseases 12 99, No. 1. Co-trimoxazole Septrin 960 mg bd 2×/week is the agent of choice for the prevention of PCP infection in those who can tolerate it. 43, 63 However, because of the theoretical concern of myelosuppression, prophylaxis regimens typically avoid co-trimoxazole use prior to engraftment Table 43.4. Jan 15, 2013 Cotrimoxazole was discontinued, and the man was discharged. In March 2008, cotrimoxazole was restarted. Seventeen days later, he developed a new clinical-analytical episode of hepatitis with acute renal failure. Cotrimoxazole was discontinued, and he began receiving hydroxychloroquine and doxycycline. Ebstein's anomaly), urinary tract defects, oral clefts, and club foot in epidemiological studies. Its use during the first trimester (during organogenesis) and 12 weeks prior to pregnancy has been associated with an increased risk of congenital malformations, especially malformations associated with maternal folic acid deficiency (which is most likely related to the mechanism of action of co-trimoxazole) such as neural tube defects such as spina bifida, cardiovascular malformations (e.g. Plaquenil and cotrimoxazole Co-trimoxazole MedlinePlus Drug Information, Cotrimoxazole - an overview ScienceDirect Topics Plaquenil moon faceChloroquine and osmotic lysis of endosomeChloroquine in congoChloroquine retinopathy octChloroquine and depression Cotrimoxazole Drug Information from Includes Cotrimoxazole side effects, interactions and indications. Cotrimoxazole Drug Information, Professional. Cotrimoxazole, Reactions Weekly 10.2165/00128415-201113790.. Contemporary unconventional clinical use of co-trimoxazole - ScienceDirect. Review. Cotrimoxazole, the combination of trimethoprim TMP and sulfamethoxazole SMX, is frequently required for the treatment of critically ill patients with infections caused by sensitive pathogens, such as Pneumocystis jovenii or Stenotrophomonas maltophilia. What is drug-induced skin pigmentation. Drug-induced skin pigmentation accounts for 10–20% of all cases of acquired hyperpigmentation. Pigmentation may be induced by a wide variety of drugs; the main ones implicated include non-steroidal anti-inflammatory drugs NSAIDs, phenytoin, antimalarials, amiodarone, antipsychotic drugs, cytotoxic drugs, tetracyclines, and heavy metals. For the other 10 patients, the median cumulative dose of the new formulation was 3.78 gm. Three patients had experienced previous allergic reactions to penicillin or cotrimoxazole, and 1 patient had previous allergic reactions to multiple drugs morphine, fluoxetine, carbamazepine, tramadol, and amitryptiline Table 1.