Although not all of these side effects may occur, if they do occur they may need medical attention. Check with your doctor immediately if any of the following side effects occur while taking hydroxychloroquine: Incidence not known Some side effects of hydroxychloroquine may occur that usually do not need medical attention. How does plaquenil treat arthritis Hydroxychloroquine davis In this review, we analyze Plaquenil side effects by the time on the drug, gender and age of the people who have side effects while taking Plaquenil. The review is based on 48,938 people who have side effects while taking the drug from Food and Drug Administration FDA. Common side effects Nausea and diarrhea This can often can be combatted by taking Plaquenil with food or milk. Dizziness Precautions with this side effect Do not drive, use machinery. Cramps. Headache. Dry skin. Loss of appetite. More in Eye Health. If you are taking Plaquenil to treat an inflammatory condition or malaria, you should be aware of the side effects that may occur to your eyes and vision. Plaquenil hydroxychloroquine is in a class of drugs called disease-modifying anti-rheumatic drugs, which are used to decrease inflammation, pain and joint damage. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. These side effects may go away during treatment as your body adjusts to the medicine. Side effects with plaquenil Hydroxychloroquine Side Effects, Dosage, Uses, and More, Plaquenil What You Need to Know - Kaleidoscope Fighting Lupus Does hydroxychloroquine cause eye problems Tell your doctor if any of the following side effects, as they may be indications of a more serious reaction Headache. Loss of appetite. Dizziness. Nausea. Diarrhea, vomiting, or stomach pain. Skin rash. Plaquenil Hydroxychloroquine - Side Effects, Dosage.. Plaquenil Side Effects on Your Eyes and Vision. Plaquenil Side Effects Common, Severe, Long Term -. RARE side effects If experienced, these tend to have a Severe expression A Disease With Shrinking And Weaker Muscles Called Myopathy A Disorder Of The Peripheral Nerves That Enable Movement Called. Side Effects Nausea, stomach cramps, loss of appetite, diarrhea, dizziness, or headache may occur. If any of these effects persist or worsen, notify your doctor or pharmacist promptly. Remember. Plaquenil hydroxychloroquine is an effective medication for autoimmune conditions and malaria that comes with less side effects than other DMARDs. You will likely have to take additional medications to keep your rheumatoid arthritis in control.