Her rheumatologist instructed her to undergo a baseline ocular examination prior to initiating Plaquenil (hydroxychloroquine, Sanofi-Aventis) therapy. Toxic maculopathy associated with chloroquine use was first documented in the literature five decades ago.1 In the United States, Plaquenil––an analog to chloroquine––is used to treat a variety of conditions, including rheumatoid arthritis, lupus and several distinct inflammatory disorders. Although the incidence of macular toxicity is infrequent with Plaquenil use (at a dosage of 200mg or 400mg q.d.), its visual impact can be devastating. Plaquenil malaria treatment Adverse effect of hydroxychloroquine Dose of plaquenil for sarcoid skin lesions Hydroxychloroquine tablets in hindi The issues are reading, color and night vision. Patient 2 69 year old male presents with a history of long term plaquenil use. Diagnosed with RA at age 19 now has almost no use of his hands. Has had 10 surgeries mostly joint replacements, stopped all drugs last year after a life threatening infection now starting back on therapy. At San Antonio Eye Specialists, we monitor Plaquenil patients by testing visual acuity, color vision, central visual field testing, distortion test and a thorough retina exam. If signs of retinopathy are detected, the drug is stopped and vision typically returns to normal. In some cases, vision is permanently affected. Patients with retinal changes may be asymptomatic initially, or may have scotomatous vision with paracentral, pericentral ring types, temporal scotomas, and abnormal color vision.-Corneal changes including edema and opacities can be symptomless or may cause disturbances such as haloes, blurring of vision or photophobia. They may be transient. Initially, central visual acuity may be unaffected, but the patient may notice related paracentral scotomas that often interfere with reading. The associated classic retinal toxicity is described as a bull’s eye maculopathy (ring of depigmented retinal pigment epithelium that spares the foveal area). Plaquenil and color vision Plaquenil Hydroxychloroquine Uses, Dosage, Side Effects., Plaquenil Hydroxychloroquine sulphate tablets in india Hydroxychloroquine Plaquenil is a drug that is classified as an anti-malarial drug. Plaquenil is prescribed for the treatment or prevention of malaria. It is also prescribed for the treatment of rheumatoid arthritis, lupus, and the side effects of lupus such as hair loss, joint pain, and more. Hydroxychloroquine Plaquenil Side Effects & Dosage for Malaria. Plaquenil Side Effects Common, Severe, Long Term -. Side Effects of Plaquenil Hydroxychloroquine, Warnings, Uses. The American Academy of Ophthalmology released an updated set of screening recommendations for hydroxychloroquine Plaquenil and chloroquine to account for the many studies that have shown the effects of these medications on the retina 1. It succinctly makes the case for screening, and A Change In Vision; Acquired Chromatopsia, A Change In Color Vision; Irritability; Loss Of Muscle Coordination; Low Energy; Mood Changes; Muscle Tremors; Muscle Weakness; Nightmares Plaquenil Side Effects on Your Eyes and Vision If you are taking Plaquenil to treat an inflammatory condition or malaria, you should be aware of the side effects that may occur to your eyes and vision.