Several years of treatment to suppress the immune system may be necessary to achieve these results. Those who don’t recover completely may need to continue on at least a low dose of medication to control the autoimmune attack of dermatomyositis throughout their lives. Hydroxychloroquine autophagy Is there withdrawal from hydroxychloroquine Plaquenil 200 mg daily Hydroxychloroquine also known by its popular brand name Plaquenil is an oral medication that is commonly used to treat a variety of autoimmune diseases including systemic lupus, dermatomyositis, rheumatoid arthritis, Sjogren’s and many other conditions as well. In the field of hair loss, conditions such as lichen planopilaris, frontal fibrosing alopecia and discoid lupus are frequently treated with hydroxychloroquine. This cohort study used 111 patients with dermatomyositis treated with hydroxychloroquine. Out of this number, 23 experienced an associated adverse cutaneous event. According to the study, in patients who had a skin eruption, 7 had anti–small ubiquitinlike modifier 1 activating enzyme autoantibodies vs 7 of 88 patients without a skin eruption. Prednisone is the first-line therapy for muscle involvement in dermatomyositis. The dose is altered according to the response of the patient’s condition. Antimalarials, particularly hydroxychloroquine, may be useful for cutaneous disease; however, the majority of patients with cutaneous involvement require additional. The chart below describes the common treatments for dermatomyositis and how they work. Drugs that suppress the immune system are the mainstay of therapy. Plaquenil for dermatomyositis Dermatomyositis - NORD National Organization for Rare Disorders, Hydroxychloroquine in Dermatomyositis What Do Skin Eruptions. Plaquenil withdrawal symptoms Dermatomyositis DM is a collagen vascular disease with prominent cutaneous findings. Although the myositis often responds to therapy with corticosteroids and/or immunosuppressives, the cutaneous disease may not respond. Cutaneous lesions of dermatomyositis are improved by.. Dermatomyositis Medication Disease-Modifying Antirheumatic.. Dermatomyositis - NORD National Organization for Rare.. Nov 01, 2001 Heliotrope, a macular rash with periorbital edema, is considered a characteristic finding of dermatomyositis, as are periungual telangiectasias Figure 2. 1,8 The rash occurs early in the course of the disease in 30 to 60 percent of patients. Generally, Plaquenil is a treatment option as monotherapy used alone for mild rheumatoid arthritis or as combination therapy with other DMARDs for moderate to severe disease. A Bit of History The origin of antimalarials dates back to the 1630s in Peru. The bark from the "fever tree' was found to contain the antimalarial compound, quinine. Dermatomyositis is found among people who take Plaquenil, especially for people who are female, 60+ old, have been taking the drug for 1 - 6 months, also take medication Rituxan, and have Pain.