Chloroquine has been extensively used in mass drug administrations, which may have contributed to the emergence and spread of resistance. It is recommended to check if chloroquine is still effective in the region prior to using it. Diseases treated with plaquenil How long does it take for plaquenil to start working Chloroquine and primaquine malaria Chloroquine diphosphate salt C6628 - Product Information Sheet Author Sigma-Aldrich Corp. Subject This product is a member of the quinoline family with multiple applications. It was originally used as an antimalarial compound. The drug should be administered with caution to patients having G-6-PD glucose-6 phosphate dehydrogenase deficiency. In patients with preexisting auditory damage, chloroquine should be administered with caution. In case of any defects in hearing, chloroquine should be immediately discontinued, and the patient closely observed. The Chloroquine base also goes by the name; 7-chloro-4-4- diethylamino-1-methylbutylamino quinolone. The most commonly available version of the drug for aquarium use is the diphosphate salt. This compound is a fine white fine powder that is readily soluble in water. The Centers for Disease Control and Prevention recommend against treatment of malaria with chloroquine alone due to more effective combinations. In areas where resistance is present, other antimalarials, such as mefloquine or atovaquone, may be used instead. Chloroquine phosphate solubility Chloroquine Dosage Guide with Precautions -, Chloroquine Phosphate - Antirheumatic Agents, Antimalarials. Hydroxychloroquine & cholesterol-lowering medication Chloroquine phosphate, USP is a 4-aminoquinoline compound for oral administration. It is a white crystalline powder; odorless; has a bitter taste, and is discolored slowly on exposure to light. It is freely soluble in water, practically insoluble in alcohol, in chloroform and in ether. Chloroquine phosphate, USP is an antimalarial and. DailyMed - CHLOROQUINE PHOSPHATE- chloroquine phosphate.. Aquarium Fish Chloroquine A "New" Drug for Treating Fish.. Chloroquine Phosphate - ScienceDirect. Chloroquine is an aminoquinolone derivative first developed in the 1940s for the treatment of malaria. It was the drug of choice to treat malaria until the development of newer antimalarials such as pyrimethamine, artemisinin, and mefloquine. Chloroquine was granted FDA Approval on 31 October 1949. Chloroquine is a 4-aminoquinoline with antimalarial, anti-inflammatory, and potential chemosensitization and radiosensitization activities. Although the mechanism is not well understood, chloroquine is shown to inhibit the parasitic enzyme heme polymerase that converts the toxic heme into non-toxic hemazoin, thereby resulting in the accumulation of toxic heme within the parasite. Chloroquine phosphate tablets 250 mg, chloroquine phosphate, USP, is a 4-aminoquinoline compound for oral administration. It is a white, odorless, bitter tasting, crystalline substance, freely soluble in water. Chloroquine phosphate is an antimalarial and amebicidal drug.