It may have both an anti-spirochaete activity and an anti-inflammatory activity, similar to the treatment of rheumatoid arthritis. And caution is required if patients have certain heart conditions, diabetes, psoriasis etc. Monitoring hydroxychloroquine Plaquenil and risperdal Jun 18, 2015 Interestingly, as described for hydroxychloroquine, auranofin was shown to disrupt in various cell lines the TLR-4 signaling, which is activated by bacterial lipopolysaccharides and likely constitutes another source of immune hyperactivation. Jan 13, 2010 An immune system modulator is a component that either increases or decreases the effectiveness of your immune functions and cells. There are many reasons why this process is used, and there are many benefits to using immune modulation instead of antibiotics or other drugs. Sometimes this method is used in addition to other recognized procedures. It is not clear why hydroxychloroquine is effective at treating autoimmune diseases. It is believed that hydroxychloroquine interferes with the communication of cells in the immune system. The most serious adverse effects affect the eye, with dose-related retinopathy as a concern even after hydroxychloroquine use is discontinued. The most common adverse effects are a mild nausea and occasional stomach cramps with mild diarrhea. Is hydroxychloroquine an immune modulator Can plaquenil hydroxychloroquine for autoimmune disease., What Is an Immune System Modulator? Plaquenil side effects constipationPrednisone vs plaquenil Hydroxychloroquine. Hydroxychloroquine is an antimalarial drug with antiinflammatory effects and often is used for maintenance therapy for autoimmune conditions. Although its mechanism of action is unclear, multiple studies have demonstrated no evidence of teratogenicity. Immune Modulating Therapies in Pregnancy and Lactation - ACOG. Hydroxychloroquine Plaquenil. Chloroquine and beyond exploring. - PubMed Central PMC. So interestingly I've heard the mechanism behind what makes the disease so dangerous is that it triggers a very severe immune response. So if you have heightened immune response already then no bueno, but if you are immunocompromised like infants and pregnant women are the illness is less severe. Hydroxychloroquine HCQ, sold under the brand name Plaquenil among others, is a medication used for the prevention and treatment of certain types of malaria. Specifically it is used for chloroquine-sensitive malaria. Other uses include treatment of rheumatoid arthritis, lupus, and porphyria cutanea tarda. It is taken by mouth. May 22, 2017 Hydroxychloroquine This is a mild immune modulator drug that decreases inflammation. Disease-modifying antirheumatic drugs Abbreviated as DMARDs, these drugs also suppress the immune system.