It may have both an anti-spirochaete activity and an anti-inflammatory activity, similar to the treatment of rheumatoid arthritis. And caution is required if patients have certain heart conditions, diabetes, psoriasis etc. Using chloroquine to treat glioblastoma How to get off hydroxychloroquine Plaquenil skin Dosage for Plaquenil. The adult dose of Plaquenil to suppress malaria is 400 mg on the same day each week. The pediatric weekly suppressive dosage is 5 mg/kg of body weight. The adult dose of Plaquenil to treat an acute attack of malaria is an initial dose of 800 mg followed by 400 mg in six to eight hours and 400 mg for two more days. Hydroxychloroquine Plaquenil is a drug that is classified as an anti-malarial drug. Plaquenil is prescribed for the treatment or prevention of malaria. It is also prescribed for the treatment of rheumatoid arthritis, lupus, and the side effects of lupus such as hair loss, joint pain, and more. Hydroxychloroquine Plaquenil® is a 4-amino-quinoline antimalarial medication that is widely used to treat systemic lupus erythematosus SLE, rheumatoid arthritis, and related inflammatory and dermatological conditions. It is a hydroxylated version of chloroquine, with a similar mechanism of action. However, following an identical dose of. The most serious adverse effects affect the eye, with dose-related retinopathy as a concern even after hydroxychloroquine use is discontinued. The most common adverse effects are a mild nausea and occasional stomach cramps with mild diarrhea. Oral plaquenil Hydroxychloroquine Oral Route Before Using - Mayo Clinic, Hydroxychloroquine Plaquenil Side Effects & Dosage for Malaria Plaquenil cost for genericDoes plaquenil cure lupus Side Effects. Drug information provided by IBM Micromedex Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention. Hydroxychloroquine Oral Route Side Effects - Mayo Clinic. Hydroxychloroquine DermNet NZ. Plaquenil Hydroxychloroquine Uses, Dosage, Side Effects.. What is Plaquenil? Plaquenil hydroxychloroquine is a medication most known for its original purpose of treating or preventing malaria, a disease caused by parasites that enter the body through the bite of a mosquito. Pharmacokinetics Following a single 200 mg oral dose of Plaquenil to healthy male volunteers, the mean peak blood concentration of hydroxychloroquine was 129.6 ng/mL, reached in 3.26 hours with a half-life of 537 hours 22.4 days. In the same study, the plasma peak concentration was 50.3 ng/mL reached in 3.74 hours with a half-life of 2963. Hydroxychloroquine Plaquenil is considered a disease-modifying anti-rheumatic drug DMARD. It can decrease the pain and swelling of arthritis. It may prevent joint damage and reduce the risk of long-term disability. Hydroxychloroquine is in a class of medications that was first used to prevent and treat malaria.